FOR INDEPENDENT WORK OF STUDENTS WITH TUTOR

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Course: 4

Discipline: Risk estimation to the health of population

From chemical contamination of environmental objects

Compilers:

Doctor of medicine, professor Kenesaryiev U.I.

Candidate of medicine, associate professor Amrin М.К.,

Candidate of medicine, associate professor Dosmukhametov А.Т.,

Almaty, 2015

Ratified on meeting of department

Pr. № _____ from __________2015

Head of department

doctor of medicine, Professor U.I. Kenesaryiev

1. Theme: Methods of collection and analysis of state information environment and health of population.

2. Aim: Forming of knowledge about general principles sanitary examination and hygienical estimation of quality food goods.

3. Educational tasks:

Forming for the students of knowledge:

- about the methods of collection and analysis of state information environment;

- about the methods of collection and analysis of state information health of population.

Forms of realization: In small groups, discussion, presentation.

5. Tasks by theme:

1. Work with recommendable literary sources.

2. Information generators about the harmful action of analysable compounds.

3. Forming of list of priority substances.

4. Information about the potential pollutants of водоисточников.

5. Information about possible contaminations of drinking-water.

6. Analysis of possible contamination of soil.

7. System of the permanent watching a nutriture.

8. Methods of collection and analysis of data on demographic indicators.

9. Methods of collection and analysis of data on the indexes of morbidity.

6. Distributing material: methodical recommendations, materials of presentation

7. Literature:

1. Kenesaryiev U.I., Balmakhaeva R.M., Bekmagambetova Zh.D., Zhakashov N.Zh., Toguzbayeva K.K.. Hygiene: Textbook for institutions of higher learning / Under printing U.I. Kenesaryiev. – Almaty: «Самара-Принт», 2009. - 688 p.

2. Тulebayev R.К., Slazhneva Т.I., Kenesaryiev U.I., Belonog А.А., Korchevskii А.А. An estimation of hygienical risks is in the industrial regions Republic of Kazakhstan. – Almaty: Искандер, 2004. – 374 p.

3. Guidance for Human Health Risk Assessment at influence of chemicals contaminating an environment (Р 2.1.10.1920-04), it is ratified by the Main state health-officer RF 05.03.2004 (Guidelines for Human Health Risk Assessment from Environmental Chemicals).

4. Onishenko G.G., Novikov S.М., Rachmanin Y.А., Avaliani S.L., Bushtueva K.А. Bases of risk estimation for the health of population at influence of chemicals contaminating an environment / Under printing Rachmanin Y.А., Onishenko G.G. М.: SRI EH and GE, 2002. - 408 p.

5. Avaliani S.L., Revich B.А., Balter B.М., Gildenskiold S.R., Mishina А.L., Kliushina E.G. Estimation of risk of contamination of environment for the health of population as an instrument of municipal ecological politics is in the Moscow area. Podolsk, 2010. - 309 p.

6. Hygiene /Under printing acad. of RАМS G.I. Rumyancev. - М.: ГЭОТАР MEDICINE, 2000.-608p.

7. Law of Republic of Kazakhstan: " About a health of people of Republic of Kazakhstan" care, " About sanitary-epidemiology prosperity population of Republic of Kazakhstan". 2007.

Control questions

1. Information about the harmful action of analysable compounds.

2. Forming of list of priority substances.

3. Information about the potential pollutants of water sources.

4. Information about possible contaminations of drinking-water.

5. Analysis of possible contamination of soil.

6. System of the permanent nutrition monitoring.

7. Methods of collection and analysis of data on demographic indicators.

8. Methods of collection and analysis of data on the indexes of morbidity.

1. Theme: Hazard identification of water and atmospheric air. Selection of priority substances.

2. Aim: Forming knowledge about hazard identification of water and atmospheric air.

3. Tasks of educating:

Forming for the students of knowledge:

- about hazard authentication of atmospheric air pollution;

- about hazard authentication of water pollution.

4. Form of realization: In small groups, case-study, discussions, presentations.

5. Tasks by theme:

1. Necessary information for realization of authentication of contamination of atmospheric air hazard.

2. Necessary information for realization of authentication of contamination of water hazard;

3. Calculation of coefficients of danger.

4. Ranging of compounds.

5. Characterization of неопределенностей on the stage of authentication of danger.

6. Distributing material: Guidance Human Health Risk Assessment from chemical contamination (Р 2.1.10.1920-04); materials of presentation.

7. Literature:

3. Kenesaryiev U.I., Zhakashov N.Zh. Ecology and human health: Textbook for medical Institutions of higher learning and colleges. Almaty. 2002.- 260 p.

4. Guidance for Human Health Risk Assessment at influence of chemicals contaminating an environment (Р 2.1.10.1920-04), it is ratified by the Main state health-officer RF 05.03.2004 (Guidelines for Human Health Risk Assessment from Environmental Chemicals).

5. Onishenko G.G., Novikov S.М., Rachmanin Y.А., Avaliani S.L., Bushtueva K.А. Bases of risk estimation for the health of population at influence of chemicals contaminating an environment / Under printing Rachmanin Y.А., Onishenko G.G. М.: SRI EH and GE, 2002. - 408 p.

6. Avaliani S.L., Revich B.А., Balter B.М., Gildenskiold S.R., Mishina А.L., Kliushina E.G. Estimation of risk of contamination of environment for the health of population as an instrument of municipal ecological politics is in the Moscow area. Podolsk, 2010. - 309 p.

7. Hygiene /Under printing acad. of RАМS G.I. Rumyancev. - М.: ГЭОТАР MEDICINE, 2000.-608p.

8. Law of Republic of Kazakhstan: " About a health of people of Republic of Kazakhstan" care, " About sanitary-epidemiology prosperity population of Republic of Kazakhstan". 2007.

8. Control questions:

1. Necessary information for realization of authentication of contamination of atmospheric air hazard.

2. Necessary information for realization of authentication of contamination of water hazard;

3. Calculation of coefficients of danger.

4. Ranging of compounds.

5. Classification of the International agency on the study of chasse;

6. Classification of degree of well-proven of cancerogenicity for a man U.S. EPA;

7. Factors of carcinogenic potential for peroral and inhalation ways of receipt;

8. Characterization of неопределенностей on the stage of authentication

1. Theme: Methods of exposure assessment due to atmospheric air. Methods of exposure assessment due to a water factor.

2. Aim: Forming of knowledge about the methods of estimation of display due to atmospheric air and water.

3. Tasks of educating:

Forming for the students of knowledge:

- about exposure assessment by the atmospheric air;

- about exposure assessment by water.

4. Form of realization: In small groups, discussions, presentations.

5. Tasks by theme:

1. Calculation of size of receipt of chemical substance with atmospheric air.

2. Calculation of size of receipt of chemical substance with water.

3. Calculations of middle daily allowance doses.

6. Distributing material: Guidance Human Health Risk Assessment from chemical contamination (Р 2.1.10.1920-04); materials of presentation.

7. Literature:

3. Kenesaryiev U.I., Zhakashov N.Zh. Ecology and human health: Textbook for medical Institutions of higher learning and colleges. Almaty. 2002.- 260 p.

7. Hygiene /Under printing acad. of RАМS G.I. Rumyancev. - М.: ГЭОТАР MEDICINE, 2000.-608p.

8. Law of Republic of Kazakhstan: " About a health of people of Republic of Kazakhstan" care, " About sanitary-epidemiology prosperity population of Republic of Kazakhstan". 2007.

Control questions

1. Sources and mechanisms of receipt of chemical substance in an environment;

2. Perceiving(initially contaminated), transporting and influencing environments;

3. it is a place of potential contact of man with a muddy environment(a point of influence/is a receptor point);

4. Ways of receipt at the contact of man with a chemical substance – per oral, inhalation, skin absorption at the consumption of water, foodstuffs, breathing and through the cutaneous covering.

5. Calculation of size of receipt of chemical substance with atmospheric air.

6. Calculation of size of receipt of chemical substance with water.

7. Calculation of middle daily allowance doses.

1. Theme: Border control 1.

2. Aim: Forming of knowledge on bases of methodology of risk and authentication of danger

Tasks of educating.

- forming of knowledge about methodology of Risk Assessment;

- forming of knowledge about basic terms and determinations;

- forming of knowledge about the stages of Risk Assessment.

- forming of knowledge about identification of hazard

4. Form of realization: In small groups, discussions, presentations.

Control questions

- A concept of environment;

- Basic objects of environment;

- Factors of environment;

- Basic indexes of human health;

- Concept about the socially-hygienical monitoring;

- Concept about methodology of Risk Assessment;

- Basic determinations and terms;

- Advantages of methodology of Risk Assessment;

- Stages of Risk Assessment and short characterization.

- Determination of danger;

- The stage of hazard identification;

- Screening estimation;

- Necessary information for realization of hazard identification;

- Uncertainties.

- Work with recommendable literary sources.

- Information generators about the harmful action of analysable compounds.

- Forming of list of priority substances.

- Information about the potential pollutants of водоисточников.

- Information about possible contaminations of drinking-water.

- Analysis of possible contamination of soil.

- System of the permanent watching a nutriture.

- Methods of collection and analysis of data on demographic indicators.

- Methods of collection and analysis of data on the indexes of morbidity.

- Necessary information for realization of authentication of contamination of atmospheric air hazard.

- Necessary information for realization of authentication of contamination of water hazard;

- Calculation of coefficients of danger.

- Ranging of compounds.

- Characterization of vagueness on the stage of authentication of danger.

6. Distributing material: materials of presentation.

7. Literature:

3. Kenesaryiev U.I., Zhakashov N.Zh. Ecology and human health: Textbook for medical Institutions of higher learning and colleges. Almaty. 2002.- 260 p.

7. Hygiene /Under printing acad. of RАМS G.I. Rumyancev. - М.: ГЭОТАР MEDICINE, 2000.-608p.

8. Law of Republic of Kazakhstan: " About a health of people of Republic of Kazakhstan" care, " About sanitary-epidemiology prosperity population of Republic of Kazakhstan". 2007.

1. Theme: Exposure assessment of chemical contaminations of food goods on a population.

2. Aim: Forming of knowledge about the exposure assessment of food goods contaminants on a population.

3. Aim of educating:

Forming for the students of knowledge:

- about the order of the use of basic data for the calculation of display from contaminants in food goods

- about the stages of exposure assessment with contaminants of food goods.

- about the rules of selection of mean values and median of maintenance of contaminants in food foods

- about the calculation of display of contaminants of food foods on a population.

- about the estimation of results of calculation of display chemical contaminants of food foods on a population.

4. Form of realization: In small groups, discussions, presentations, decision of case-study.

5. Tasks by theme:

1. Calculate exposure of food goods contaminants on a population.

2. To estimate the contribution of product to the common value of contaminants exsposure.

6. Distributing material: Collection of tasks as evaluated by the risk of influence of chemical contaminants of food foods on a population.

7. Literature:

3. Kenesaryiev U.I., Zhakashov N.Zh. Ecology and human health: Textbook for medical Institutions of higher learning and colleges. Almaty. 2002.- 260 p.

7. Hygiene /Under printing acad. of RАМS G.I. Rumyancev. - М.: ГЭОТАР MEDICINE, 2000.-608p.

8. Law of Republic of Kazakhstan: " About a health of people of Republic of Kazakhstan" care, " About sanitary-epidemiology prosperity population of Republic of Kazakhstan". 2007.

Control questions

- it is order of the use of basic data for the calculation of display from contaminants in food goods

- data used about maintenance of contaminants in food goods.

- data about the consumption of food goods a population.

- data about the consumption of food goods a population are used.

- stages of estimation of display with contaminants of food goods.

- rules of selection of mean values and median of maintenance of contaminants in food goods

- it is Calculation of display of contaminants of food goods on a population.

- it is Contribution of product to the common value of contaminants exposure.

- it is Estimation of results of calculation of display chemical contaminants of food goods on population.

1. Theme: Characteristic of carcinogenic and non-carcinogenic risks.

2. Aim: Forming knowledge and skills by risk characterization.

3. Tasks of educating:

Forming for the students of knowledge:

- about characterization of carcinogenic risks;

- about characterization of uncarcinogenic risks;

- about classification of levels of risks.

4. Form of realization: In small groups, discussions, presentations.

5. Tasks by theme:

- it is Estimation of risk of carcinogenic effects

- it is Estimation of risk of uncarcinogenic effects at sharp and chronic influences.

- it is Classification of risk levels.

6. Distributing material: Guidelines for Human Health Risk Assessment from Environmental Chemicals (Р 2.1.10.1920-04); presentation materials.

7. Literature:

3. Kenesaryiev U.I., Zhakashov N.Zh. Ecology and human health: Textbook for medical Institutions of higher learning and colleges. Almaty. 2002.- 260 p.

7. Hygiene /Under printing acad. of RАМS G.I. Rumyancev. - М.: ГЭОТАР MEDICINE, 2000.-608p.

8. Law of Republic of Kazakhstan: " About a health of people of Republic of Kazakhstan" care, " About sanitary-epidemiology prosperity population of Republic of Kazakhstan". 2007.

Control questions

- it is Estimation of risk of carcinogenic effects

- it is Estimation of risk of non-carcinogenic effects at sharp and chronic influences.

- it is risk Estimation at different media, combined and complex influences.

- it is Classification of risk levels.

- it is Generalization of information about risks.

- it is the Comparative estimation of risks.

- are Factors influencing on reliability of risk estimations.

1. Theme: Border control 2.

2. Aim: Forming of knowledge on the stages of risk estimation: dependence " dose/concentration-response", exposure, risk characterization.

Tasks of educating.

- it is forming of knowledge about dependence " dose/concentration-response";

- it is forming of knowledge about of exposure;

- it is forming of knowledge about risk characterization;

4. Form of realization: In small groups, discussions, presentations.

Control questions

1. it is a concept about the stage of estimation of dependence " dose/concentration - response";

2. it is an additional(attributive) risk;

3. it is a relative risk;

4. it is an additional population risk;

5. it is an additional stake of population risk;

6. are parameters of estimation of non-carcinogenic risks;

7. it is application of referent levels of influence;

8. are parameters of estimation of carcinogenic risks;

9. it is an analysis of uncertainties on the stage of estimation of dependence " dose/concentration - response"

10. it is a choice of parameters of dependence a " dose - response" for the estimation of risk.

11. it is estimation of exposure, determination and basic concepts.

12. the first stage of exposure estimation is characterization by influence zone

13. the second stage of exposure estimation is ways of distribution of chemicals in an environment and their affecting man.

14. it is route of influence/way of chemical substance

15. processes of transfer, accumulation and transformation of chemicals in an environment. Media distribution.

16. the third stage of exposure estimation is determination of influence degree (quantitative characterization of exposure);

17. it is determination of concentrations in the point of influence;

18. monitoring of environment objects;

19. it is design of chemicals distribution in an environment;

20. it is characterization of concentrations in the point of influence

21. exposure and doses

22. it is Calculation of daily allowance doses

23. it is order of the use of basic data for the calculation of display from contaminants in food goods

24. data used about maintenance of contaminants in food goods.

25. data about the consumption of food goods a population are used.

26. stages of estimation of display with contaminants of food goods.

27. rules of selection of mean values and median of maintenance of contaminants in food goods

28. it is Calculation of display of contaminants of food goods on a population.

29. it is Contribution of product to the common value of contaminants exposure.

30. it is Estimation of results of calculation of display chemical contaminants of food goods on population.

31. it is Estimation of risk of carcinogenic effects

32. it is Estimation of risk of non-carcinogenic effects at sharp and chronic influences.

33. it is risk Estimation at different media, combined and complex influences.

34. it is Classification of risk levels.

35. it is Generalization of information about risks.

36. it is the Comparative estimation of risks.

37. are Factors influencing on reliability of risk estimations.

6. Distributing material: materials of presentation.

7. Literature:

3. Kenesaryiev U.I., Zhakashov N.Zh. Ecology and human health: Textbook for medical Institutions of higher learning and colleges. Almaty. 2002.- 260 p.

7. Hygiene /Under printing acad. of RАМS G.I. Rumyancev. - М.: ГЭОТАР MEDICINE, 2000.-608p.

8. Law of Republic of Kazakhstan: " About a health of people of Republic of Kazakhstan" care, " About sanitary-epidemiology prosperity population of Republic of Kazakhstan". 2007.

Speciality: Public Health

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